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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ORC1L
All Species:
20.91
Human Site:
S421
Identified Species:
38.33
UniProt:
Q13415
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13415
NP_004144.2
861
97350
S421
A
E
I
S
D
S
S
S
D
E
E
E
A
S
T
Chimpanzee
Pan troglodytes
XP_513408
861
97367
S421
S
E
I
S
D
S
S
S
D
E
E
E
A
S
T
Rhesus Macaque
Macaca mulatta
XP_001111614
860
97440
S420
A
E
I
S
E
S
S
S
D
E
E
E
A
S
T
Dog
Lupus familis
XP_532575
858
97161
S419
A
E
I
S
D
S
S
S
E
E
E
E
T
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1N2
840
95057
E400
G
D
D
R
D
Q
E
E
E
E
S
V
D
S
E
Rat
Rattus norvegicus
Q80Z32
848
95741
S408
V
E
V
S
D
S
S
S
E
E
E
D
E
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026457
858
96850
S419
S
S
S
E
E
E
D
S
D
V
S
C
T
P
E
Frog
Xenopus laevis
NP_001081806
886
99953
D447
K
E
T
C
T
P
S
D
S
E
E
E
N
E
Q
Zebra Danio
Brachydanio rerio
NP_956227
910
101179
V470
D
E
E
L
E
A
K
V
D
S
E
D
E
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O16810
924
103263
S485
E
D
Y
S
P
K
K
S
V
Q
K
T
P
T
R
Honey Bee
Apis mellifera
XP_392056
490
55682
K67
S
N
M
Y
K
R
I
K
I
S
S
T
K
K
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798977
905
100707
A458
K
S
L
T
G
K
K
A
T
P
E
H
A
A
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_567440
809
91877
S381
E
E
S
V
R
G
V
S
K
S
K
R
G
G
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
94.7
81.5
N.A.
66
69.8
N.A.
N.A.
50.5
52.4
48.6
N.A.
33.4
31.8
N.A.
29.7
Protein Similarity:
100
98.9
97.3
88.8
N.A.
77.9
79.9
N.A.
N.A.
66.3
67
63.1
N.A.
52.7
43.5
N.A.
47.1
P-Site Identity:
100
93.3
93.3
86.6
N.A.
20
60
N.A.
N.A.
13.3
33.3
20
N.A.
13.3
0
N.A.
20
P-Site Similarity:
100
100
100
93.3
N.A.
33.3
80
N.A.
N.A.
26.6
33.3
40
N.A.
40
13.3
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
0
0
0
0
8
0
8
0
0
0
0
31
8
8
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
8
16
8
0
39
0
8
8
39
0
0
16
8
0
0
% D
% Glu:
16
62
8
8
24
8
8
8
24
54
62
39
16
8
16
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
8
8
0
0
0
0
0
0
8
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
31
0
0
0
8
0
8
0
0
0
0
0
0
% I
% Lys:
16
0
0
0
8
16
24
8
8
0
16
0
8
8
0
% K
% Leu:
0
0
8
8
0
0
0
0
0
0
0
0
0
8
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
8
% N
% Pro:
0
0
0
0
8
8
0
0
0
8
0
0
8
8
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
8
% Q
% Arg:
0
0
0
8
8
8
0
0
0
0
0
8
0
0
8
% R
% Ser:
24
16
16
47
0
39
47
62
8
24
24
0
0
47
0
% S
% Thr:
0
0
8
8
8
0
0
0
8
0
0
16
16
8
39
% T
% Val:
8
0
8
8
0
0
8
8
8
8
0
8
0
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _